Article
Utilizing HapMap and tagging SNPs.
Methods in molecular medicine - 1 Jan 2008
Haiman Christopher A, Stram Daniel O
Abstract excerpt
Advancements in our understanding of variation in the human genome and rapid improvements in high-throughput genotyping technology have made it feasible to study most of the human genetic diversity that is due to common variations in relation to observable phenotypes. Over the past few years, public SNP databases have matured and empirical genome-wide SNP data, such as that generated by the International HapMap...
Topics
- Algorithms
- Chromosomes, Human, Pair 8
- Computational Biology
- Databases, Genetic
- Genome, Human
- Haplotypes
- Humans
- Linkage Disequilibrium
- Polymorphism, Single Nucleotide
- Sequence Tagged Sites