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Article

Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population.

Molecular genetics & genomic medicine - 1 Mar 2021

Ahmed Sagheer, Khan Saeed, Janjua Kholood, Imran Imran, Khan Arif Ullah

Abstract excerpt

BACKGROUND: Cytochrome P450 (CYP2B6) is an important enzyme that metabolizes about 3.0% of therapeutic drugs. Drugs metabolized mainly by CYP2B6 include artemisinin, bupropion, cyclophosphamide, efavirenz, ketamine, and methadone. The genetic polymorphisms in the CYP2B6 gene have earlier been studied in many populations, but the data are lacking for the Pakistani population. This research study aimed to determine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33599403
DOI: 10.1002/mgg3.1527
PMCID: PMC8104158

Genes

CYP2B6

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