Article
Genetic polymorphisms of CYP3A4: CYP3A4*18 allele is found in five healthy Malaysian subjects.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2007
Ruzilawati A B, Suhaimi A W Mohd, Gan S H
Abstract excerpt
BACKGROUND: Cytochrome P450 3A4 (CYP3A4) is the major cytochrome involved in metabolizing of >60% of all drugs used in humans. A number of allelic variations in CYP3A4 gene are known to affect catalytic activity including CYP3A4*4, CYP3A4*5 and CYP3A4*18. We investigated the frequencies of CYP3A4...
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