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Article

Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects.

Schizophrenia bulletin - 1 Mar 2010

van den Buuse Maarten

Abstract excerpt

In recent years, there have been huge advances in the use of genetically modified mice to study pathophysiological mechanisms involved in schizophrenia. This has allowed rapid progress in our understanding of the role of several proposed gene mechanisms in schizophrenia, and yet this research has also revealed how much still remains unresolved. Behavioral studies in genetically modified mice are reviewed with...

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Identifiers

PMID: 19900963
DOI: 10.1093/schbul/sbp132
PMCID: PMC2833124

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Source receipt: pubmed, retrieved 7 Sept 2026.

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