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Article

Autism-related behavioral abnormalities in synapsin knockout mice.

Behavioural brain research - 15 Aug 2013

Greco Barbara, Managò Francesca, Tucci Valter, Kao Hung-Teh, Valtorta Flavia, Benfenati Fabio

Abstract excerpt

Several synaptic genes predisposing to autism-spectrum disorder (ASD) have been identified. Nonsense and missense mutations in the SYN1 gene encoding for Synapsin I have been identified in families segregating for idiopathic epilepsy and ASD and genetic mapping analyses have identified variations in the SYN2 gene as significantly contributing to epilepsy predisposition. Synapsins (Syn I/II/III) are a multigene...

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Source

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Identifiers

PMID: 23280234
DOI: 10.1016/j.bbr.2012.12.015
PMCID: PMC3730181

Genes

SYN1
SYN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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