Article
Positive association between synapsin II and schizophrenia.
Biological psychiatry - 1 Aug 2004
Chen Qi, He Guang, Wang Xiao Yan, Chen Qing Ying, Liu Xin Min, Gu Zhong Zhong, Liu Jie, Li Ke Qing, Wang Shi Ji, Zhu Shao Ming, Feng Guo Ying, He Lin
Abstract excerpt
BACKGROUND: Synapsin II encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The expressions of messenger ribonucleic acid and protein of synapsin II have been reported to be significantly reduced in the brains of schizophrenia patients. The synapsin II gene is located on 3p25, a region that has been implicated to be associated with...
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