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Article

The pharmacokinetics of codeine and its metabolites in Blacks with sickle cell disease.

European journal of clinical pharmacology - 1 Jul 2009

Shord Stacy S, Cavallari Larisa H, Gao Weihua, Jeong Hyun-Young, Deyo Kelly, Patel Shitalben R, Camp Joseph R, Labott Susan M, Molokie Robert E

Abstract excerpt

PURPOSE: We conducted a prospective, open-label study in 54 adult subjects with sickle cell disease to determine the relationship between morphine concentrations, cytochrome P450 (CYP) 2D6 genotype, and clinical outcomes. METHODS: A blood sample was obtained for genotyping and serial blood samples were drawn to measure codeine and its metabolites in the plasma before and after oral codeine sulfate 30 mg. Codeine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anemia, Sickle Cell

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Source

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Identifiers

PMID: 19357842
DOI: 10.1007/s00228-009-0646-3
PMCID: PMC3775655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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