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Article

The impact of cellular networks on disease comorbidity.

Molecular systems biology - 1 Jan 2009

Park Juyong, Lee Deok-Sun, Christakis Nicholas A, Barabási Albert-László

Abstract excerpt

The impact of disease-causing defects is often not limited to the products of a mutated gene but, thanks to interactions between the molecular components, may also affect other cellular functions, resulting in potential comorbidity effects. By combining information on cellular interactions, disease-gene associations, and population-level disease patterns extracted from Medicare data, we find statistically...

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Identifiers

PMID: 19357641
DOI: 10.1038/msb.2009.16
PMCID: PMC2683720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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