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Article

Discovering comorbid diseases using an inter-disease interactivity network based on biobank-scale PheWAS data.

Bioinformatics (Oxford, England) - 1 Jan 2023

Nam Yonghyun, Jung Sang-Hyuk, Yun Jae-Seung, Sriram Vivek, Singhal Pankhuri, Byrska-Bishop Marta, Verma Anurag, Shin Hyunjung, Park Woong-Yang, Won Hong-Hee, Kim Dokyoon

Abstract excerpt

MOTIVATION: Understanding comorbidity is essential for disease prevention, treatment and prognosis. In particular, insight into which pairs of diseases are likely or unlikely to co-occur may help elucidate the potential relationships between complex diseases. Here, we introduce the use of an inter-disease interactivity network to discover/prioritize comorbidities. Specifically, we determine disease associations...

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PMID: 36571484
DOI: 10.1093/bioinformatics/btac822
PMCID: PMC9825330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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