Article
Biomechanisms of Comorbidity: Reviewing Integrative Analyses of Multi-omics Datasets and Electronic Health Records.
Yearbook of medical informatics - 10 Nov 2016
Pouladi N, Achour I, Li H, Berghout J, Kenost C, Gonzalez-Garay M L, Lussier Y A
Abstract excerpt
OBJECTIVES: Disease comorbidity is a pervasive phenomenon impacting patients' health outcomes, disease management, and clinical decisions. This review presents past, current and future research directions leveraging both phenotypic and molecular information to uncover disease similarity underpinning the biology and etiology of disease comorbidity. METHODS: We retrieved ~130 publications and retained 59, ranging...
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