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Article

Role for interleukin-6 in COPD-related pulmonary hypertension.

Chest - 1 Sept 2009

Chaouat Ari, Savale Laurent, Chouaid Christos, Tu Ly, Sztrymf Benjamin, Canuet Matthieu, Maitre Bernard, Housset Bruno, Brandt Christian, Le Corvoisier Philippe, Weitzenblum Emmanuel, Eddahibi Saadia, Adnot Serge

Abstract excerpt

BACKGROUND: Pulmonary artery remodeling triggered by alveolar hypoxia is considered the main mechanism of pulmonary hypertension (PH) in COPD patients. We hypothesized that the risk for PH in COPD is increased by an elevation in the proinflammatory cytokines interleukin (IL)-6, monocyte chemoattractant protein-1 (MCP-1), and IL-1beta, as well as by specific genetic polymorphisms of these cytokines. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19349390
DOI: 10.1378/chest.08-2420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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