Article
Interaction between smoking and the interleukin-6 gene affects systemic levels of inflammatory biomarkers.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Nov 2009
Sunyer Jordi, Forastiere F, Pekkanen J, Plana E, Kolz M, Pistelli R, Jacquemin B, Brüske-Hohlfeld I, Pitsavos Ch, Bellander T, Koenig W, Peters A
Abstract excerpt
BACKGROUND: Smoking is associated with a systemic inflammatory response. However, the role of genetic predisposition is not well known. We assessed whether circulatory acute phase reactants were associated with smoking and whether or not the association was modified by the major cytokine gene of the acute phase reaction, interleukin-6 (IL-6). METHODS: In total, 1,003 postmyocardial infarction patients were...
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