Article
Association of IL-6 gene polymorphisms and COPD in a Spanish population.
Respiratory medicine - 1 Dec 2008
Córdoba-Lanús Elizabeth, de-Torres Juan-Pablo, López-Aguilar Celeste, Rodríguez-Pérez María-Cristo, Maca-Meyer Nicole, Montejo-de-Garcini Angela, Aguirre-Jaime Armando, Pérez-Méndez Lina, Casanova Ciro
Abstract excerpt
Interleukin-6 (IL-6) is a potential mediator of systemic effects of Chronic Obstructive Pulmonary Disease (COPD). In the present case-control study we investigated the association of promoter polymorphisms of this gene and COPD in a cohort of 191 patients, smokers without COPD (n=75) and a healthy control population (n=296). Besides spirometry, exercise capacity (6MWD, 6 min walking distance) and body mass index...
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