Article
Regulation of Hox gene activity by transcriptional elongation in Drosophila.
Current biology : CB - 28 Apr 2009
Chopra Vivek S, Hong Joung-Woo, Levine Michael
Abstract excerpt
Hox genes control the anterior-posterior patterning of most metazoan embryos. Their sequential expression is initially established by the segmentation gene cascade in the early Drosophila embryo [1]. The maintenance of these patterns depends on the Polycomb group (PcG) and trithorax group (trxG) complexes during the remainder of the life cycle [2]. We provide both genetic and molecular evidence that the Hox genes...
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