Article
The GAGA factor is required in the early Drosophila embryo not only for transcriptional regulation but also for nuclear division.
Development (Cambridge, England) - 1 Apr 1996
Bhat K M, Farkas G, Karch F, Gyurkovics H, Gausz J, Schedl P
Abstract excerpt
The GAGA protein of Drosophila was first identified as a stimulatory factor in in vitro transcription assays using the engrailed and Ultrabithorax promoters. Subsequent studies have suggested that the GAGA factor promotes transcription by blocking the repressive effects of histones; moreover, it has been shown to function in chromatin remodeling, acting together with other factors in the formation of nuclease...
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