Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo.

Proceedings of the National Academy of Sciences of the United States of America - 8 Jun 1999

Mannervik M, Levine M

Abstract excerpt

Previous studies have implicated histone deacetylation and chromatin condensation as critical mechanisms of transcription repression in yeast and mammals. A specific histone deacetylase, Rpd3, interacts with a variety of sequence-specific transcriptional repressors, including Mad-Max heterodimers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Histone Deacetylase 1

Share to Histone Deacetylases

Share to Repressor Proteins

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 10359792
DOI: 10.1073/pnas.96.12.6797
PMCID: PMC21995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10359792-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo.PMID 10359792Read ↗

Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.Semantic proximity Read ↗

Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo.Semantic proximity Read ↗

Foxd3 is an essential Nodal-dependent regulator of zebrafish dorsal mesoderm development.Semantic proximity Read ↗

The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability.Semantic proximity Read ↗

Multiple regulatory elements direct the complex expression pattern of the Drosophila segmentation gene paired.Semantic proximity Read ↗

The Drosophila DAXX-Like Protein (DLP) Cooperates with ASF1 for H3.3 Deposition and Heterochromatin Formation.Semantic proximity Read ↗

Transcriptional adaptor ADA3 of Drosophila melanogaster is required for histone modification, position effect variegation, and transcription.Semantic proximity Read ↗

dRYBP counteracts chromatin-dependent activation and repression of transcription.Semantic proximity Read ↗

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.Semantic proximity Read ↗

A screen for modifiers of Deformed function in Drosophila.Semantic proximity Read ↗

Epigenetic regulation of the Drosophila chromosome 4 by the histone H3K9 methyltransferase dSETDB1.Semantic proximity Read ↗

Paf1 complex homologues are required for Notch-regulated transcription during somite segmentation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.