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Article

Somatic hypermutation in peritoneal B1b cells.

Molecular immunology - 1 May 2009

Roy Bishnudeo, Shukla Swati, Łyszkiewicz Marcin, Krey Martina, Viegas Nuno, Düber Sandra, Weiss Siegfried

Abstract excerpt

Murine B1 cells have been shown to be able to switch to IgA in vitro. In agreement, we could demonstrate in the peritoneum of mice the presence of IgA producing B1 cells. Interestingly, enzyme-linked immunospot assays of lipopolysaccharide stimulated cultures revealed that only the B1b cell subpopulation contained high numbers of such cells while IgA producing B cells were rare amongst the B2 and B1a cell...

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Share to B-Lymphocytes
Share to Immunoglobulin A
Share to Immunoglobulin Variable Region

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19327839
DOI: 10.1016/j.molimm.2009.02.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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