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Article

Intestinal IgA plasma cells of the B1 lineage are IL‐5 dependent

14 Jun 1998

Abstract excerpt

Two lineages of B cells, designated B1 and B2 cells, have been identified based upon their origins, anatomical distribution, cell surface markers, antibody repertoire and self-replenishing potential. B1 cells are maintained by self-renewal of cells resident in the peritoneal cavity (PerC) and they utilize a limited repertoire of germline V-region genes, mostly directed against ubiquitous bacterial antigens such...

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PMID: 9741339
DOI: 10.1046/j.1365-2567.1998.00512.x

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