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Article

Molecular comparison of cultured hybridoma cells that switch isotypes at high and low rates.

Somatic cell and molecular genetics - 1 Jul 1996

Lin M, Spira G, Scharff M D

Abstract excerpt

We have previously reported the isolation of variants from the 36.65 and PC1.4.1 hybridoma cell lines that spontaneously switch from gamma 1 to gamma 2a and gamma 2b at high and low rates. In order to further characterize the phenotype of these variants, we have now investigated the production of germline transcripts and methylation which are two of the molecular correlates of isotype switching. While some of the...

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PMID: 9000175
DOI: 10.1007/BF02369570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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