Article
B-1a cell origin of the murine B lymphoma line BCL1 characterized by surface markers and bacterial reactivity of its surface IgM.
Immunology letters - 15 May 2005
Koganei Satoru, Ito Masayuki, Yamamoto Kazuo, Matsumoto Naoki
Abstract excerpt
B cells are divided into two categories: conventional or B-2B cells and B-1B cells, the latter of which are distinguished by their different ontogeny. B cell lymphoma 1 (BCL1), the first-reported case of a spontaneously developed mouse B-lymphoma, expresses CD5, surface IgM, Mac-1, CD43 and low level of B220, and is likely to have B-1a cell origin. However, antigens recognized by IgM produced by the BCL1 cells...
Topics
- Animals
- Antibodies, Bacterial
- Antibodies, Monoclonal
- Antigens, Differentiation
- B-Lymphocytes
- Base Sequence
- Cell Line, Tumor
- Cell Lineage
- Epitopes, B-Lymphocyte
- Escherichia coli
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Light Chains
- Immunoglobulin M
