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Article

CD14 promoter-159 polymorphism is associated with reduced risk of intestinal-type gastric cancer in a Japanese population.

Digestive diseases and sciences - 1 Jul 2009

Tahara Tomomitsu, Shibata Tomoyuki, Hirata Ichiro, Nakano Hiroshi, Arisawa Tomiyasu

Abstract excerpt

Host genetic factors may play a key role in determining the long-term outcome of the Helicobacter pylori infection. Toll-like receptor 4 (TLR4) and CD14-mediated recognition of lipo-polysaccharide (LPS) is required for efficient recognition of gram-negative bacterial infections. We investigated the effects of common polymorphisms of TLR4 Asp299Gly, Thr399Ile, and CD14 promoter-C159T on the risk of gastric cancer...

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Source

Identifiers

PMID: 19326213
DOI: 10.1007/s10620-009-0793-5

Genes

TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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