Article
Functional polymorphisms of CD14 and toll-like receptor 4 in Taiwanese Chinese with Helicobacter pylori-related gastric malignancies.
Hepato-gastroenterology - 1 Jan 2000
Wu Ming-Shiang, Cheng Tsu-Yao, Shun Chia-Tung, Lin Ming-Tsan, Chen Li-Chong, Lin Jaw-Town
Abstract excerpt
BACKGROUND/AIMS: Interindividual differences in degrees and extent of gastritis are responsible for the divergent outcomes after H. pylori infection. Cellular responses in gastric inflammation are mediated by lipopolysaccharide of H. pylori, which activate monocytes to express cytokine expression and growth factors via CD14 and toll-like receptor 4 (TLR4). Whether functional polymorphisms of TLR 4 and CD14...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
