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Article

Association between TLR4 (+896A/G and +1196C/T) polymorphisms and gastric cancer risk: an updated meta-analysis.

PloS one - 1 Jan 2014

Zhou Quan, Wang Chenchen, Wang Xiaofeng, Wu Xiongyan, Zhu Zhenggang, Liu Bingya, Su Liping

Abstract excerpt

BACKGROUND: Toll-like receptor 4 (TLR4) is a receptor of lipopolysaccharide in the signaling transduction of gastric epithelial cell. It plays a pivotal role in activation of innate immunity and pathogen recognition and thus acts as a modulator in the development and progression of gastric cancer. Growing studies explored the association of polymorphisms in TLR4 with susceptibility to gastric cancer, but the...

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Identifiers

PMID: 25290654
DOI: 10.1371/journal.pone.0109605
PMCID: PMC4188729

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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