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Article

Polymorphisms of the TLR2 and TLR4 genes are associated with risk of gastric cancer in a Brazilian population.

World journal of gastroenterology - 21 Mar 2012

de Oliveira Juliana Garcia, Silva Ana Elizabete

Abstract excerpt

AIM: To investigate toll-like receptor 2 (TLR2) -196 to -174 del, and TLR4 (+896A/G rs4986790 and +1196C/T rs4986791) polymorphisms at risk of chronic gastritis and gastric cancer in a Brazilian population and association of gastric lesions with risk factors such as smoking, alcohol intake and Helicobacter pylori infection. METHODS: In this case-control study, polymorphism at TLR2 -196 to -174 del was...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Brazil
Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Genetic Predisposition to Disease

Genotype

Humans

Male

Middle Aged

Polymorphism, Single Nucleotide

Stomach Neoplasms

Toll-Like Receptor 2

Toll-Like Receptor 4

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 22468087
DOI: 10.3748/wjg.v18.i11.1235
PMCID: PMC3309913

Genes

TLR4
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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