Article
Role of CD14 promoter polymorphisms in Helicobacter pylori infection--related gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2007
Zhao Dan, Sun Tong, Zhang Xuemei, Guo Yongli, Yu Dianke, Yang Ming, Tan Wen, Wang Guiqi, Lin Dongxin
Abstract excerpt
PURPOSE: Genetic variation in CD14 may affect CD14 expression and susceptibility to Helicobacter pylori infection-related cancers. This study examined functional single nucleotide polymorphisms (SNP) in the CD14 promoter and their associations with risk of developing gastric carcinoma in relation to H. pylori infection. EXPERIMENTAL DESIGN: Thirty individual DNAs were sequenced to identify variants, and the...
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