Article
Treatment- and population-dependent activity patterns of behavioral and expression QTLs.
PloS one - 1 Jan 2012
Ziebarth Jesse D, Cook Melloni N, Wang Xusheng, Williams Robert W, Lu Lu, Cui Yan
Abstract excerpt
Genetic control of gene expression and higher-order phenotypes is almost invariably dependent on environment and experimental conditions. We use two families of recombinant inbred strains of mice (LXS and BXD) to study treatment- and genotype-dependent control of hippocampal gene expression and behavioral phenotypes. We analyzed responses to all combinations of two experimental perturbations, ethanol and...
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