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Article

DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies.

Genome biology - 1 Jan 2007

Hovatta Iiris, Zapala Matthew A, Broide Ron S, Schadt Eric E, Libiger Ondrej, Schork Nicholas J, Lockhart David J, Barlow Carrolee

Abstract excerpt

BACKGROUND: Expression quantitative trait locus (eQTL) mapping is used to find loci that are responsible for the transcriptional activity of a particular gene. In recent eQTL studies, expression profiles were derived from either homogenized whole brain or collections of large brain regions. However, the brain is a very heterogeneous organ, and expression profiles of different brain regions vary significantly....

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Identifiers

PMID: 17324278
DOI: 10.1186/gb-2007-8-2-r25
PMCID: PMC1852412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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