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Allele dose analysis in recombinant inbred strains: a tool for multiple phenotype analysis with implications for quantitative trait loci mapping.

Alcoholism, clinical and experimental research - 1 Apr 1999

Markel P D, Erwin V G

Abstract excerpt

A considerable investment in genetic mapping is necessary to confirm linkages of quantitative trait loci for complex traits such as ethanol sensitivity, a significant predictor of alcoholism. Before embarking on such intensive mapping efforts in large intercrosses, we suggest an approach based on genetic marker data in recombinant strains that yield a rationale for selecting a battery of related phenotypes for...

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PMID: 10235295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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