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Article

Association of the (TAAAA)n repeat polymorphism in the sex hormone-binding globulin (SHBG) gene with polycystic ovary syndrome and relation to SHBG serum levels.

The Journal of clinical endocrinology and metabolism - 1 Dec 2003

Xita Nectaria, Tsatsoulis Agathocles, Chatzikyriakidou Anthi, Georgiou Ioannis

Abstract excerpt

SHBG levels are frequently low in women with polycystic ovary syndrome (PCOS) and may contribute to increased tissue exposure to free androgens. A (TAAAA)n repeat polymorphism in the promoter of the SHBG gene has been described recently, and its transcriptional activity has been shown to be related to the number of tandem repeats. Recent evidence also suggests that prenatal exposure to androgen excess may program...

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Source

Identifiers

PMID: 14671199
DOI: 10.1210/jc.2003-030197

Genes

SHBG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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