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Article

A common polymorphism in the human aromatase gene alters the risk for polycystic ovary syndrome and modifies aromatase activity in vitro.

Molecular human reproduction - 1 Jun 2011

Wang Hui, Li Qiaoli, Wang Teng, Yang Guizhong, Wang Ying, Zhang Xiaoping, Sang Qing, Wang Huan, Zhao Xinzhi, Xing Qinghe, Shi Juanzi, He Lin, Wang Lei

Abstract excerpt

Aromatase is a key enzyme involved in estradiol and estrone biosynthesis. Given that polymorphisms of the CYP19A1 gene encoding aromatase have been correlated with plasma testosterone levels, CYP19A1 may therefore act as a genetic modifier of the hyperandrogenic phenotype of polycystic ovary synd...

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PMID: 21282199
DOI: 10.1093/molehr/gar007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21282199-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A common polymorphism in the human aromatase gene alters the risk for polycystic ovary syndrome and modifies aromatase activity in vitro.PMID 21282199Read ↗

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