Article
Positional effect of mutations in 5'UTR of hepatitis C virus 4a on patients' response to therapy.
World journal of gastroenterology - 28 Mar 2009
El Awady Mostafa-K, Azzazy Hassan-M, Fahmy Ahmed-M, Shawky Sherif-M, Badreldin Noha-G, Yossef Samar-S, Omran Moataza-H, Zekri Abdel-Rahman-N, Goueli Said-A
Abstract excerpt
AIM: To investigate the effects of mutations in domain III of the hepatitis C virus (HCV) internal ribosome entry sequences (IRES) on the response of chronic HCV genotype 4a patients to interferon therapy. METHODS: HCV RNA was extracted from 19 chronic HCV 4a patients receiving interferon/ribavirin therapy who showed dramatic differences in their response to combination therapy after initial viral clearance. IRES...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
