Article

Impact of virus subtype and host <i>IFNL4</i> genotype on large-scale RNA structure formation in the genome of hepatitis C virus

2020-06-17

Abstract excerpt

<h4>ABSTRACT</h4> Mechanisms underlying the ability of hepatitis C virus (HCV) to establish persistent infections and induce progressive liver disease remain poorly understood. HCV is one of several positive-stranded RNA viruses capable of establishing persistence in their immunocompetent vertebrate hosts, an attribute associated with formation of large scale RNA structure in their genomic RNA. We developed novel...

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Literature Corpus work: 821dfa2a-031b-59dc-b0f6-e65443f273f9
DOI: 10.1101/2020.06.16.155150

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