Article
6q23 polymorphisms in rheumatoid arthritis Spanish patients.
Rheumatology (Oxford, England) - 1 Jun 2009
Perdigones Nieves, Lamas José Ramón, Vigo Ana G, de la Concha Emilio G, Jover Juan Angel, Urcelay Elena, Gutiérrez Benjamín-Fernández, Martínez Alfonso
Abstract excerpt
OBJECTIVE: The aim of this work is to replicate the role of two recently described RA genetic markers (rs10499194 and rs6920220) situated at 6q23 in the autoantibody-positive phenotype. METHODS: A case-control study (630 RA patients and 664 healthy blood donors, all white Spaniards) was performed with two single nucleotide polymorphisms (rs6920220 and rs10499194) situated at 6q23. Genotyping was performed by...
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