Article
Genetic polymorphisms in Spanish rheumatoid arthritis patients: an association and linkage study.
Genes and immunity - 1 Mar 2003
Martinez A, Pascual M, Pascual-Salcedo D, Balsa A, Martin J, de la Concha E G
Abstract excerpt
HLA polymorphism accounts only for approximately one-third of the genetic predisposition to rheumatoid arthritis (RA). To investigate the role of other loci in the susceptibility to RA, we have performed an analysis of several polymorphisms in genes of immune-related function: IL-10 -1082, -819, -592 promoter single nucleotide polymorphisms (SNPs), IL-10G and IL-10R microsatellites, IL-6 -622 promoter SNP,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
