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Article

Identification of a cis-acting element involved in the regulation of BACE1 mRNA alternative splicing.

Journal of neurochemistry - 1 May 2009

Mowrer Karen R, Wolfe Michael S

Abstract excerpt

beta-site APP cleaving enzyme 1 (BACE1) is the transmembrane aspartyl protease that catalyzes the first cleavage step during proteolysis of the beta-amyloid precursor protein, a process involved in the pathogenesis of Alzheimer disease. BACE1 pre-mRNA undergoes complex alternative splicing, and c...

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Source

Identifiers

PMID: 19302194
DOI: 10.1111/j.1471-4159.2009.06026.x

Genes

BACE1
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19302194-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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