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Article

Association studies using novel polymorphisms in BACE1 and BACE2.

Neuroreport - 3 Jul 2001

Nowotny P, Kwon J M, Chakraverty S, Nowotny V, Morris J C, Goate A M

Abstract excerpt

The release of amyloid-beta peptide (Abeta) from beta-amyloid precursor protein (APP) requires cleavage by beta- and gamma-secretases. Several groups have identified a candidate for the beta-site APP-cleaving enzyme, BACE1, and its homologue BACE2. We sequenced the genes for BACE1 and BACE2 and f...

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Share to Amyloid beta-Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11435901
DOI: 10.1097/00001756-200107030-00008

Genes

BACE1
BACE2
APP
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11435901-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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