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Minigene reporter for identification and analysis of cis elements and trans factors affecting pre-mRNA splicing.

BioTechniques - 1 Aug 2006

Singh Gopal, Cooper Thomas A

Abstract excerpt

All human genes contain a diverse array of cis-acting elements within introns and exons that are required for correct and efficient precursor messenger RNA (pre-mRNA) splicing. Recent computational analyses predict that most human exons contain elements required for splicing coinciding with an appreciation for the high frequency with which mutations that disruption pre-mRNA splicing cause disease. Minigenes...

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PMID: 16925019
DOI: 10.2144/000112208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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