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Article

An association of prodynorphin polymorphisms and opioid dependence in females in a Chinese population.

Addiction biology - 1 Jul 2009

Clarke Toni-Kim, Krause Kristina, Li Tao, Schumann Gunter

Abstract excerpt

Prodynorphin (PDYN) binds to kappa-opioid receptors and is known to regulate dopaminergic tone, making this system important for the reinforcing and rewarding properties of drugs of abuse such as opioids. The binding of dynorphins to kappa-opioid receptors also produces aversive states that may a...

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Source

Identifiers

PMID: 19298317
DOI: 10.1111/j.1369-1600.2009.00151.x

Genes

PDYN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19298317-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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