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Article

A molecular prospective provides new insights into implication of PDYN and OPRK1 genes in alcohol dependence.

Computers in biology and medicine - 1 Oct 2014

Faisal Muhammad, Waseem Durdana, Ismatullah Humaira, Taqi Malik Mumtaz

Abstract excerpt

Single nucleotide polymorphisms (SNPs) both in coding and non-coding regions govern gene functions prompting differential vulnerability to diseases, heterogeneous response to pharmaceutical regimes and environmental anomalies. These genetic variations, SNPs, may alter an individual׳s susceptibility for alcohol dependence by remodeling DNA-protein interaction patterns in prodynorphin (PDYN) and the κ-opioid...

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Source

Identifiers

PMID: 25177835
DOI: 10.1016/j.compbiomed.2014.07.021

Genes

OPRK1
PDYN
NFYA
TBP
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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