Impaired Cholesterol Biosynthesis in a Neuronal Cell Line Persistently Infected with Measles Virus

Abstract excerpt

Measles virus remains a substantial cause of morbidity and mortality, producing acute infection with a potential for development of viral persistence. To study the events underlying acute and persistent measles virus infection, we performed a global transcriptional analysis on murine neuroblastoma cells that were acutely or persistently infected with measles virus. In general, we found that acute infection...

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