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Metabolic reprogramming and lipid droplets are involved in Zika virus replication in neural cells

8 Mar 2023

Abstract excerpt

Zika virus (ZIKV) infection is a global public health concern linked to adult neurological disorders and congenital diseases in newborns. Host lipid metabolism, including lipid droplet (LD) biogenesis, has been associated with viral replication and pathogenesis of different viruses. However, the mechanisms of LD formation and their roles in ZIKV infection in neural cells are still unclear. Here, we demonstrate...

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PMID: 36882750
DOI: 10.1186/s12974-023-02736-7

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