Article
Measles virus induces persistent infection by autoregulation of viral replication.
Scientific reports - 24 Nov 2016
Doi Tomomitsu, Kwon Hyun-Jeong, Honda Tomoyuki, Sato Hiroki, Yoneda Misako, Kai Chieko
Abstract excerpt
Natural infection with measles virus (MV) establishes lifelong immunity. Persistent infection with MV is likely involved in this phenomenon, as non-replicating protein antigens never induce such long-term immunity. Although MV establishes stable persistent infection in vitro and possibly in vivo, the mechanism by which this occurs is largely unknown. Here, we demonstrate that MV changes the infection mode from...
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