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Article

A global lipid map defines a network essential for Zika virus replication

21 Jul 2020

Abstract excerpt

Zika virus (ZIKV), an arbovirus of global concern, remodels intracellular membranes to form replication sites. How ZIKV dysregulates lipid networks to allow this, and consequences for disease, is poorly understood. Here, we perform comprehensive lipidomics to create a lipid network map during ZIKV infection. We find that ZIKV significantly alters host lipid composition, with the most striking changes seen within...

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PMID: 32694525
DOI: 10.1038/s41467-020-17433-9

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