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Perturbation of <i>de novo</i> lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles

2024-08-23

Abstract excerpt

Coronaviruses hijack host cell metabolic pathways and resources to support their replication. They induce extensive host endomembrane remodeling to generate viral replication organelles and exploit host membranes for assembly and budding of their enveloped progeny virions. Because of the overall significance of host membranes, we sought to gain insight into the role of host factors involved in lipid metabolism in...

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Literature Corpus work
aea1b402-8de1-5fe9-8d66-6c3f4ea98b20
DOI
10.1101/2024.08.21.608937
Open publication

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Perturbation of <i>de novo</i> lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organellesDOI 10.1101/2024.08.21.608937
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