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Influenza A Virus Mediated Downregulation of Progesterone Receptor Membrane Component-1 Inhibits RIG-I-dependent Antiviral Response in Central Nervous System

2020-10-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The influenza A virus (IAV) enters the central nervous system (CNS) via multiple routes and causes neurological symptoms. In this process, it develops multiple strategies to escape the host anti-viral immune system, and infects the central nervous system (CNS). Progesterone receptor membrane component-1 (PGRMC1) is highly expressed in the CNS, where it exerts a...

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Literature Corpus work
5da238a1-e7d6-5b47-8b9e-7a4b71e9778a
DOI
10.21203/rs.3.rs-90902/v1
Open publication

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Influenza A Virus Mediated Downregulation of Progesterone Receptor Membrane Component-1 Inhibits RIG-I-dependent Antiviral Response in Central Nervous SystemDOI 10.21203/rs.3.rs-90902/v1
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