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Article

Regulation of the catalytic activity of herpes simplex virus 1 protein kinase Us3 by autophosphorylation and its role in pathogenesis.

Journal of virology - 1 Jun 2009

Sagou Ken, Imai Takahiko, Sagara Hiroshi, Uema Masashi, Kawaguchi Yasushi

Abstract excerpt

Us3 is a serine/threonine protein kinase encoded by herpes simplex virus 1 (HSV-1). We recently identified serine at Us3 position 147 (Ser-147) as a physiological phosphorylation site of Us3 (A. Kato, M. Tanaka, M. Yamamoto, R. Asai, T. Sata, Y. Nishiyama, and Y. Kawaguchi, J. Virol. 82:6172-6189, 2008). In the present study, we investigated the effects of phosphorylation of Us3 Ser-147 on regulation of Us3...

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Identifiers

PMID: 19297494
DOI: 10.1128/JVI.00103-09
PMCID: PMC2681960

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of the catalytic activity of herpes simplex virus 1 protein kinase Us3 by autophosphorylation and its role in pathogenesis.PMID 19297494Read ↗

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