Article
Roles of the Different Isoforms of the Pseudorabies Virus Protein Kinase pUS3 in Nuclear Egress.
Journal of virology - 17 Mar 2020
Sehl Julia, Pörtner Sandy, Klupp Barbara G, Granzow Harald, Franzke Kati, Teifke Jens P, Mettenleiter Thomas C
Abstract excerpt
Protein kinases homologous to the US3 gene product (pUS3) of herpes simplex virus (HSV) are conserved throughout the alphaherpesviruses but are absent from betaherpesviruses and gammaherpesviruses. pUS3 homologs are multifunctional and are involved in many processes, including modification of the cytoskeleton, inhibition of apoptosis, and immune evasion. pUS3 also plays a role in efficient nuclear egress of...
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