Article
Association of CYP1B1 haplotypes and breast cancer risk in Caucasian women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2009
Huang Yifan, Trentham-Dietz Amy, García-Closas Montserrat, Newcomb Polly A, Titus-Ernstoff Linda, Hampton John M, Chanock Stephen J, Haines Jonathan L, Egan Kathleen M
Abstract excerpt
CYP1B1 is a key enzyme involved in estrogen metabolism and may play an important role in the development and progression of breast cancer. In a population-based case-control study, we examined eight CYP1B1 haplotype-tagging single nucleotide polymorphisms in relation to invasive breast cancer risk. Analyses were based on 1,655 cases and 1,470 controls; all women were Caucasian. Among the individual single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
