Article
Association of cytochrome P450 1B1 haplotypes with head and neck cancer risk.
Environmental and molecular mutagenesis - 1 Jul 2017
Katiyar Tridiv, Maurya Shailendra S, Hasan Feza, Singh Arvind P, Khan Anwar J, Hadi Rahat, Singh Sudhir, Bhatt Madan L B, Parmar Devendra
Abstract excerpt
Genetic polymorphisms have been reported in several cytochrome P450 (CYP) genes, including CYP1B1 which metabolically activates procarcinogens present in tobacco to carcinogenic intermediates. This study used a case-control approach in North Indian population to determine associations between genetic variants in CYP1B1 and risk of Head and Neck Squamous Cell Carcinoma (HNSCC). We examined the genotype and...
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