Article
CYP1B1 variants are associated with prostate cancer in non-Hispanic and Hispanic Caucasians.
Carcinogenesis - 1 Sept 2008
Beuten Joke, Gelfond Jonathan A L, Byrne John J, Balic Ivana, Crandall AnaLisa C, Johnson-Pais Teresa L, Thompson Ian M, Price Douglas K, Leach Robin J
Abstract excerpt
Cytochrome P450 1B1 (CYP1B1) is involved in the activation of many carcinogens and in the metabolism of steroid hormones. We compared allele, genotype and haplotype frequencies of six single-nucleotide polymorphisms (SNPs) within CYP1B1 among non-Hispanic Caucasians (496 cases and 498 controls) and Hispanic Caucasians (153 cases and 240 controls). In the Hispanic Caucasians, the GG genotype for rs1056836...
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